Resource circulation and digital transformation (DX) have become crucial concepts for sustainable development in the 21st century. Achieving effective resource circulation is an urgent goal due to its critical contribution to the SDGs, as well as its legal and commercial advantages in the industry. DX-related science and technology in research of materials and chemicals are frequently referred to as Materials DX in Japan, a key concept in research on materials and chemicals. Utilizing Materials DX is essential to reduce the development period of a wide variety of new materials and chemicals. This symposium aims to facilitate interdisciplinary communication in the field of materials and chemistry by integrating state-of-the-art knowledge on technologies for resource circulation and new approaches to accelerate materials and chemical development through so-called Materials DX. The scope of the symposium covers both academic and industrial topics in related fields. This includes advanced recycling technology for metallic and plastic materials, chemical recycling of plastics, and the circulation of carbon, nitrogen, hydrogen, phosphorus, and other elemental resources. Topics on new artificial intelligence (AI)-assisted approaches to reduce the development period of new materials and chemicals for various clean energy applications (e.g., lightweight materials, permanent magnets, batteries, solar cells, cellulose nanofiber, etc.) are also strongly encouraged.